Mumps virus infection

Like other infections, there is a theoretical risk that mumps during the early months of pregnancy may cause complications. Most studies on the effects of gestational mumps on the fetus were conducted in the s—60s when the disease was more common before mumps vaccine was available. One study from reported an association between mumps infection during the first trimester of pregnancy and an increase in the rate of spontaneous abortion or intrauterine fetal death 1 , but this result has not been observed in other studies 2.

One study of low birth weight in relation to mumps during pregnancy found no significant association 1. While there are case reports of congenital malformations in infants born to mothers who had mumps during pregnancy, the only prospective, controlled study found rates of malformations were similar between mothers who had mumps and those who did not have mumps during pregnancy 3. Learn more about preventing infections during pregnancy.

People who previously had one or two doses of MMR vaccine can still get mumps and transmit the disease. During mumps outbreaks in highly vaccinated communities, the proportion of cases that occur among people who have been vaccinated may be high. This does not mean that the vaccine is ineffective. The effectiveness of the vaccine is assessed by comparing the attack rate in people who are vaccinated with the attack rate in those who have not been vaccinated.

In outbreaks of highly vaccinated populations, people who have not been vaccinated against mumps usually have a much greater mumps attack rate than those who have been fully vaccinated. Disease symptoms are generally milder and complications are less frequent in vaccinated people. Vaccination is the best way to prevent mumps and mumps complications. In October , the Advisory Committee on Immunization Practices ACIP recommended that people identified by public health authorities as being part of a group at increased risk for acquiring mumps because of a mumps outbreak should receive a third dose of MMR vaccine.

The purpose of the recommendation is to improve protection of people in outbreak settings against mumps disease and mumps-related complications. See Mumps Vaccination for vaccination recommendations.

RT-PCR and viral culture are used to confirm mumps infection. IgM serology can also be used to aid in diagnosing mumps infection. Overview Salivary glands Open pop-up dialog box Close. Salivary glands You have three pairs of major salivary glands — parotid, sublingual and submandibular. Mumps Open pop-up dialog box Close. Mumps Mumps is characterized by swollen, painful salivary glands in the face, causing the cheeks to puff out. Request an Appointment at Mayo Clinic.

Share on: Facebook Twitter. Show references Kliegman RM, et al. In: Nelson Textbook of Pediatrics. Philadelphia, Pa. Accessed July 14, Centers for Disease Control and Prevention. Rochester, Minn. Accessed July 13, Ramanathan R, et al. Knowledge gaps persist and hinder progress in eliminating mumps.

Ferri FF. In: Ferri's Clinical Advisor We excluded the articles that were not published in the English language, manuscripts without abstracts, and opinion articles from the review. The number of cases caused by MuV decreased steeply after the introduction of the mumps vaccine worldwide. In recent years, a global resurgence of mumps cases in developed countries and cases of aseptic meningitis caused by some mumps vaccine strains have renewed the importance of MuV infection worldwide.

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